How is it that we were able to vaccinate the Ebola virus so quickly?

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Mudassir Ali 9 months 1 Answer 132 views

Answer ( 1 )

  1. Quickly here depends on what you are comparing it to? The first case of Ebola virus dated back to 1976. And between 1976 and 1998 over 30,000 mammals, birds, reptiles, amphibians etc. from outbreak regions have been tested for Ebola virus.

    And as of today there is no vaccine or treatment licensed to counteract Ebola. Although, several viral vector approaches, replicating and non replicating, have been tested as potential vaccine platforms and their protective efficacy has been evaluated in nonhuman primate models for Ebola virus infections, which closely resemble disease progression in humans. Though these vaccine platform seem to confer protection through different mechanism, several of them are efficacious against lethal disease in nonhuman primates attesting that vaccination against Ebola virus infections is feasible (informahealthcare.com).

    Recently many vaccines have been discovered mainly because of the potential risks of Ebola virus globally especially in Europe and America. Ebola hemorrhagic fever is one of the most fatal viral diseases worldwide affecting humans and nonhuman primates. So far most cases of Ebola infections have been in Central & West Africa (in other word contained and not too important to the western world), however the virus has the potential to spread globally (scary part; especially in Europe with big cities where people travel easily and freely) and it could be used as a bioterrorism agent.

    IMO the following two reasons have been the drive behind the recent discoveries of Ebola virus vaccines:
    Ebola virus use as bioterrorism agent (imagine if Ebola go airborne? Theoretical possible but a very long shot because viruses like Ebola don’t have the protein attachments that can actually attach to cells in the upper airway) and
    Ebola virus outbreaks extend to Europe and Other continents with fatality rate of up to 90% – we’re talking about global cataclysm (surely, there will be more fatality in the West – big cities compared to little village in Central Africa).

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