Is Ebola a coronavirus?

Mudassir Ali
Mar 11, 2020 11:01 AM 0 Answers
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Mudassir Ali
- Mar 11, 2020 11:01 AM

No. These virus types are quite different.

Below is an ebolavirus – a zoonotic hemorrhagic fever virus associated with high case fatality rate (35–90%) when it jumps from animal reservoirs into human hosts.

Below is a coronavirus. Many forms of common cold viruses are coronaviruses, but the agents of SARS and MERS outbreaks are also coronaviruses, with CFR around 15–30%. The SARS and MERS coronaviruses are also zoonoses but they target the respiratory system.

No effective vaccine or treatment has yet been approved for either virus, although several Ebola vaccines are being tried in DRC with great promise.

In 2015, Mingo et al. found that, surprisingly, both EBOV and SARSV delay entry for about 30 minutes into the host cell for replication. They do so to access high levels of cathepsin, a protease enzyme that the viruses use in their fusion-triggering mechanisms. This unexpected similarity suggests an unexplored vulnerability that may indicate a way to structure an antiviral.

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