Why does Ebola kill?

Mudassir Ali
Mar 10, 2020 06:48 PM 0 Answers
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Mudassir Ali
- Mar 10, 2020 06:48 PM

Actually an inside thing between me and a few friends is related to reasons why “pathogens” kill at all. It is not beneficial to them if the host die since they die with the host. It is why that diseases with a low mortality rate, or not as pathogenic/quickly lethal spread the most efficiently, because the host lives to keep passing it on to more hosts.

When someone dies to a disease, it is rarely because the virus has killed all the cells it has infected, like say Ebola which target the liver cells. You don’t die because Ebola has successfully destroyed your liver. Or the endothelia Cells, you don’t die because The Virus has killed all of that.

Another example, how about HIV, in simple terms it infects white blood cells, but you don’t die from missing white blood cells, you die from infections that overwhelm you because you are missing white blood cells.

What about rabies? You might ask, rabies kills by excitotoxicit, which overstimulates the brain and causes the cells to die, and then the patient to die, rabies can’t transfer from human to human, it is transferred by animals, so if it ends up in a human it has reached a dead end anyways.

In most cases, the patient will die due to their own immune response, that’s right, the very thing keeping you protected from these nasties are the things that end up killing you trying to save you.

Here is an example, the fever, everyone has had it before, it aids in host defense speeding up immunological reactions with it rise in temperature, and pathogens can be hindered, sometimes. But prolonged it can damage the body such as by causing brain damage or death.

Ebola also causes hemorrhage, when the person starts bleeding everywhere, it isn’t because the virus just cuts open your vessels, your own immune system is opening up blood vessels to let in fluids to help fight infection, but doing so puts your own body at risk… results speak for themselves.

Ebola also causes a cytokine storm, an over production of immune cells and their compounds, normally kept in check sometimes your body basically panics when facing a dangerous intruder so this feedback loop becomes uncontrolled. Dealing tons of damage to your own body tissues and organs.

Example, if it happens in the lungs the increased fluid and immune cells may accumulate blocking off airways and kill you…

In conclusion, it is not beneficial to a disease to kill its host, it’s also why parasites are so successful.

Your body kind of kill itself in most cases trying to defend you.

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